Lab of Computational Neuroscience

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The lab of computational neuroscience at Shanghai Jiao Tong University is directed by Douglas Zhou and Songting Li. It involves a diverse team with expertise of mathematics, physics, computer science and biology, sharing a common interest in understanding how the brain works. In general, the research in the lab applies mathematical modeling and computational techniques to investigate principles of neuronal computation across spatiotemporal scales, including dendritic computation of a single neuron, dynamics of neuronal circuitry and large-scale networks, and brain-inspired machine learning algorithms. The lab is in quest of mathematical understanding of the brain with a close collaboration with experimentalists.

news

Dec, 2025 Application and registeration of the 15th Computational Neuroscience Winter School is opening.
Nov, 2025 Paper ‘A hierarchy of time constants and reliable signal propagation in the marmoset cerebral cortex’ has been accepted online by Nature Communications.
Oct, 2025 Paper ‘Overcoming the space clamp effect: Reliable recovery of local and effective synaptic conductances of neurons’ has been accepted online by Proceedings of the National Academy of Sciences of the United States of America (PNAS).
Jul, 2025 Paper ‘Adaptive cholinergic feedback network oscillations: insights into striatal beta oscillations and circuit dynamics’ has been accepted online by Cognitive Neurodynamics.
Apr, 2025 Paper ‘A generalized Spiking Locally Competitive Algorithm for multiple optimization problems’ has been accepted online by Neurocomputing.
Jan, 2025 Paper ‘Biophysical modeling and experimental analysis of the dynamics of C. elegans body-wall muscle cells’ has been accepted online by PLOS Computational Biology.